Risk factors for postoperative morbidity after thyroid surgery in a PROSPECTIVE cohort of 1500 patients

Abstract Background Postoperative hypocalcaemia, recurrent laryngeal nerve palsy and postoperative bleeding are the most frequent complications after thyroid surgery, therefore often used as quality indicators of surgery. We aimed to assess morbidity in a high-volume endocrine surgery unit, detect which factors associated with higher risks. Methods Prospective surgical cohort tertiary referral centre for xxx. The first 1500 patients operated hemi or total thyroidectomy during 2010–2019 were included. assessed relation pre- peri-operative characteristics using multivariable logistic regression analyses, expressed odds ratios 95% confidence intervals. Results Overall, 1043 (69.5%) received 457 (30.5%) hemithyroidectomy. Permanent hypocalcaemia occurred 3.1%, permanent 1.8% reintervention 2.6%. Younger age, female sex cancer risk hypocalcaemia. No clear could be identified palsy. Female sex, high body mass index heavier thyroids protective against thyroidectomy. Conclusions Surgical experience seems beneficial clinical outcomes contributes organizational efficiency. A low complication can obtained by trained surgeons, yet is not negligible.